Prevalence and Correlation of Hyperuricemia in Diabetes Patients: A Study at a Tertiary Level Hospital in Bangladesh

Background: The prevalence of hyperuricemia (HU), which has been associated to the emergence of cardiovascular disease, high blood pressure, the metabolic syndrome, and diabetes mellitus (DM), is on the rise. Serum uric acid (SUA) elevations have been linked to an increased risk of hypertension and diabetes in many nations. However, this association has not been established in the Asia region. Objective: The aim of this study is interested in the frequency of HU and the connection between Hyperuricemia with diabetes patient. Methods: This cross-sectional study was conducted in the Department of Medicine Rajshahi medical college, Rajshahi. Three hundred-five patients with a recent diagnosis of diabetes were enrolled (212 men and 93 women). Following American Heart Association guidelines, all patients were classified as having normal or high blood pressure (140/90). Results: The average SUA level was 5.14± 0.073 mg/dl, with males having considerably greater levels than females (P<0.000). The patients' mean age, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 46.76 ±0.61 years, 130.6±1.06 mmHg and 84.11±0.63 mmHg, respectively. The overall prevalence of HU and hypertension was 12.13% and 44.59%, respectively. There was an increase in the prevalence of hypertension across the SUA tertile. SBP and DBP significantly increased across the SUA tertile (P<0.014 and <0.001, respectively). Conclusion: In Asia, this is the first study to investigate at the relationship between SUA and hypertension in diabetic people. Therefore, in newly diagnosed hypertensive diabetic patients, it is recommended to test SUA routinely to prevent HU and its related consequences.