The Importance of Pharmaceutical Excipients and their Interactions with Drug Substance During Formulation


  The Importance of Pharmaceutical Excipients and their Interactions with Drug Substance During Formulation
  Ashok Kumar
  https://doi.org/10.62469/tmb.v02i04.004
  Pdf Download
Dosage forms are accompanied by excipients to facilitate their production, administration, or absorption. Excipients can begin, propagate, or engage in chemical or physical interactions with medicinal components, even if they may appear to have no pharmacological effect. This can make a medication less effective. Not every recipient of an award is exceptionally well-groomed. It is essential to comprehend the manufacturing process of excipients, especially the most widely used ones, in order to identify possible interactions between trace components and active pharmaceutical substances. The amount of the active component that is accessible for therapeutic effect may be reduced due to degradation brought on by chemical interactions. Physical interactions can affect the rate of dissolution, dosage homogeneity, or convenience of administration.